Dynamics of EBV and the Potential for Vaccinations in the United States
Session Title
Poster Session 1
Faculty Mentor
Kristen Abernathy, Ph.D.
College
College of Arts and Sciences
Department
Mathematics
Abstract
Epstein-Barr virus (EBV) is one of the most common human viruses, with roughly 90% of the population in the United States carrying the virus by adulthood. EBV is spread through bodily fluids and infections tend to be asymptomatic, however in some cases EBV can lead to infectious mononucleosis (IM) and some cancers such as Hodgkin’s lymphoma. Currently there is no approved vaccine, but clinical trials are in development. This study presents a mathematical model of EBV transmission, calibrated using data from the United States, to compare possible vaccine strategies with varying efficacies, duration, and age of vaccination.
Previously Presented/Performed?
SAEOPP McNair/SSS Scholars Research Conference, Buckhead, GA, June 2022 | Winthrop University Showcase of Winthrop University Undergraduate Research and Creative Endeavors, Rock Hill, SC, April 2023
Type of Presentation
Poster presentation
Grant Support?
Supported by an SC-INBRE grant from the National Institute for General Medical Sciences (P20GM103499).
Start Date
15-4-2023 12:00 PM
Dynamics of EBV and the Potential for Vaccinations in the United States
Epstein-Barr virus (EBV) is one of the most common human viruses, with roughly 90% of the population in the United States carrying the virus by adulthood. EBV is spread through bodily fluids and infections tend to be asymptomatic, however in some cases EBV can lead to infectious mononucleosis (IM) and some cancers such as Hodgkin’s lymphoma. Currently there is no approved vaccine, but clinical trials are in development. This study presents a mathematical model of EBV transmission, calibrated using data from the United States, to compare possible vaccine strategies with varying efficacies, duration, and age of vaccination.
