Multiple Sclerosis and Exercise
Session Title
Other Abstracts
Faculty Mentor
Janet Wojcik, Ph.D.
College
College of Education
Department
Physical Education, Sport & Human Performance
Abstract
The central nervous system (CNS) lesions that characterize the chronic inflammatory disease known as multiple sclerosis (MS) can cause significant physical or cognitive impairments as well as neurological problems. The present data demonstrate that the origin of MS is multifaceted and includes genetic predisposition along with environmental factors such exposure to infectious agents, vitamin deficiencies, and smoking, even though the origin and pathophysiology of MS remain unknown. These substances have the capacity to start a chain reaction in the immune system that results in the death of neurons, demyelination of the nerves, and neurological dysfunction. A review of literature found on exercise in the experimental autoimmune encephalomyelitis (EAE) animal model of multiple sclerosis before summarizing the findings about the impact of exercise on particular MS symptoms and functional limitations. The most recent recommendations for safe fitness programs for MS patients are covered. Regarding the impact of exercise on EAE, rats were forced to run for 1 day after the disease was induced. In comparison to the control (sedentary) rats, the exercised rats displayed a significant delay in disease onset and a reduction in disease severity. Aerobic exercise recommendations of 5 days a week at low to moderate intensity to improve cardio fitness. These sessions should be no more than 30 minutes. Resistance training was described as twice a week of low to moderate muscular strength training, from one set of 10 to 15 repetitions with light weight. Physical activity is encouraged for patients with MS, as it has been demonstrated to be safe, well tolerated, and beneficial as the condition progresses.
Course Assignment
EXSC 511 – Wojcik
Start Date
15-4-2023 12:00 PM
Multiple Sclerosis and Exercise
The central nervous system (CNS) lesions that characterize the chronic inflammatory disease known as multiple sclerosis (MS) can cause significant physical or cognitive impairments as well as neurological problems. The present data demonstrate that the origin of MS is multifaceted and includes genetic predisposition along with environmental factors such exposure to infectious agents, vitamin deficiencies, and smoking, even though the origin and pathophysiology of MS remain unknown. These substances have the capacity to start a chain reaction in the immune system that results in the death of neurons, demyelination of the nerves, and neurological dysfunction. A review of literature found on exercise in the experimental autoimmune encephalomyelitis (EAE) animal model of multiple sclerosis before summarizing the findings about the impact of exercise on particular MS symptoms and functional limitations. The most recent recommendations for safe fitness programs for MS patients are covered. Regarding the impact of exercise on EAE, rats were forced to run for 1 day after the disease was induced. In comparison to the control (sedentary) rats, the exercised rats displayed a significant delay in disease onset and a reduction in disease severity. Aerobic exercise recommendations of 5 days a week at low to moderate intensity to improve cardio fitness. These sessions should be no more than 30 minutes. Resistance training was described as twice a week of low to moderate muscular strength training, from one set of 10 to 15 repetitions with light weight. Physical activity is encouraged for patients with MS, as it has been demonstrated to be safe, well tolerated, and beneficial as the condition progresses.
