The Proposed Formation of Acylsilanes through Tandem Nucleophilic Activation-Silylation and Retro-Brook Rearrangement
Poster Number
40
College
College of Arts and Sciences
Department
Chemistry, Physics, Geology, & the Environment
Faculty Mentor
Aaron M. Hartel, Ph.D.
Abstract
The purpose of this research project was to create a valid synthesis in which aldehydes were used to produce acylsilanes through the use of tandem nucleophilic activation-silylation and the retro-Brook rearrangement. The nucleophiles that were selected to undergo investigation consisted of cyanide and phosphonates. The temperature was varied during experimentation in correlation to the type of base and starting material used during synthesis. The overall data collected during experimentation concluded that the proposed method of synthesis was correct and the production of acylsilanes was confirmed through both 1H and 13C NMR spectroscopy.
Start Date
24-4-2015 3:20 PM
End Date
24-4-2015 4:50 PM
The Proposed Formation of Acylsilanes through Tandem Nucleophilic Activation-Silylation and Retro-Brook Rearrangement
Richardson Ballroom
The purpose of this research project was to create a valid synthesis in which aldehydes were used to produce acylsilanes through the use of tandem nucleophilic activation-silylation and the retro-Brook rearrangement. The nucleophiles that were selected to undergo investigation consisted of cyanide and phosphonates. The temperature was varied during experimentation in correlation to the type of base and starting material used during synthesis. The overall data collected during experimentation concluded that the proposed method of synthesis was correct and the production of acylsilanes was confirmed through both 1H and 13C NMR spectroscopy.
